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Study shows adherence packaging drives gains in patient persistence

Article-Study shows adherence packaging drives gains in patient persistence

Catalent Pharma Solutions has announced the results of an independent study in which unit-dose patient adherence packaging was associated with a 17-point increase in patient persistency to a drug over 12 months, as compared to conventional 30-count bottle packaging.

The study utilized patient data from SDI, the provider of anonymous patient-based prescription data. SDI's prescription coverage represents claims data from over 50% of the retail pharmacies in the United States. The claims from these pharmacies account for one half of dispensed claims across all pay types, including cash, commercial 3rd party, Medicare Part D, and Medicaid.

The adherence study looked at patient persistency rates over a 12-month period by analyzing a cohort of 200,000 qualified patients who filled their prescriptions in either a traditional bottle or a patient adherence package. Persistency rates were defined as the percentage of patients who remained compliant or restarted therapy over the 12-month tracking cycle.

"We believe that every element of dose form and package design can be selected to improve patient treatments. Previous studies have identified packaging as one of many means to increase patient adherence, but none have focused on the impact of packaging alone," stated Cornell Stamoran, vice president of strategy and corporate development at Catalent Pharma Solutions. "For the first time, we have quantified the real-world patient adherence benefit that advanced drug packaging can provide."

Unlike the conventional 30-count bottle, which is commonly used throughout North America, adherence packaging is designed with a focus on unit dosing, reminder prompting, printed instructions, time-dating and other features that enable delivery of the right dose at the right time. Adherence packaging safety is enhanced through child-resistance features, and adult-friendly attributes make the package easier for patients to open.

"At Catalent, we do not believe in the concept of ‘one size fits all' for patient adherence packaging solutions," Mr. Stamoran commented. "To truly improve patient adherence, the package must incorporate multiple adherence drivers that are customized to the needs of the specific therapeutic area."

The new study results suggest that appropriately tailored packaging can provide customers with cost-effective solutions that positively impact patient adherence and treatment outcomes. Through Catalent's proprietary child resistant and senior-friendly packaging formats, the company can provide a tailored solution to enhance each patient's experience.

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